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The sphenoid is the access bone for transsphenoidal pituitary surgery and a major landmark in skull-base operations
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The conformational constraints imposed by the disulfide bridge are central to how peptide hormones achieve specificity
oxytocin necklace 3D | gold vermeil pp_DNA The sphenoid is the accessOxytocin necklace 3D 18k gold vermeil Oxytocin is the cyclic nonapeptide that du Vigneaud synthesised in 1953, the first total synthesis of a polypeptide. The disulfide locked ring enforces the conformation that the OXTR receptor recognises. Two amino acid swaps make vasopressin out of the same chassis, which is why the two peptides cross react at low levels. The Science Behind Oxytocin Oxytocin's affiliative effects in animal models laid the
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